Is hepatitis A vaccine live or inactive

The different types of vaccines

In the case of mRNA vaccines, the human body cells are provided with the blueprint for virus proteins. In the form of the so-called "Messenger RNA". This information is read out in the cells and the encoded protein is produced. This selection is a process that takes place continuously in the body's cells in order to produce proteins that are necessary for the cell. Human cells can also produce the coronavirus spike protein (SARS-CoV-2) themselves. However, since it is a foreign protein that is unusable for the cell, it is transported to the cell surface and "presented" there with the help of so-called immune complex proteins. This is recognized by special immune cells. As a result, it stimulates the immune system to produce antibodies against SARS-COV-2 and to generate specific T cells that are directed against parts of the foreign protein.

Like all other vaccinations, an mRNA vaccination also brings a pathogen or part of it into the human body, so that the body's immune system is stimulated to produce antibodies. It differs in how pathogens (components) are transported into the body: While these are administered directly with other vaccine technologies, with mRNA vaccinations only the blueprint for certain proteins of the affected virus is produced in the laboratory and added to the vaccine. This enables cells of the human body to produce this protein or the pathogen (components) themselves. The mRNA that was administered via the vaccine is broken down by the cells after a short time. After the mRNA has been broken down, no further production of the virus protein takes place.

mRNA vaccines have been researched for over 30 years. The first mRNA vaccines approved in Europe are recently vaccines against COVID-19 from BioNTech / Pfizer and Moderna.

NoteThe mRNA cannot influence the human genome (carrier of genetic information), which consists of DNA. It is not built into DNA and has no influence on human genetic information neither in body cells nor in reproductive cells.