Helps cannabis oil with anxiety

Cannabis for anxiety and post-traumatic stress disorder

Science / Human: According to an experimental study, THC could improve the eradication of fear in anxiety disorders

THC prevented the recurrence of fear in an extinction experiment. This is the result of a placebo-controlled study with 29 healthy people at the University of Michigan Psychiatry Clinic in Ann Arbor (USA). Participants were exposed to a standard model for the extinction of fear. In this experiment of classical conditioning, a neutral stimulus, for example a sound, is followed by a second (unpleasant) stimulus, for example pain. If this experiment is repeated, the first (neutral) stimulus will already cause a physical reaction because people are expecting the pain (the second stimulus). Extinction is a learning process in which the learned response to the first stimulus disappears if that stimulus occurs without the second (unpleasant) stimulus. This absorbance learning is an important approach in treating anxiety disorders.

In the study, 14 participants received oral THC two hours before extinction, while 15 received a placebo. The subjects were retested 24 hours after the extinction. Compared to participants who received a placebo, those who received THC had better extinction of fear. THC could therefore be useful in treating anxiety disorders such as post-traumatic stress disorder. The scientists concluded that "these results provide the first evidence that pharmacological enhancement of extinction works in humans when modulators of the cannabinoid system are used. This deserves further development and clinical investigation."

Science / Human: Cannabis reduces symptoms in a patient with severe post-traumatic stress disorder

Symptoms of severe post-traumatic stress disorder were significantly improved in a young man by self-treatment with cannabis. This emerges from a case report from the Department of Psychiatry at the Hannover Medical School (Germany). Since the age of four, the patient had been the victim of long-term, sadistic sexual abuse by his father and his paternal uncle. This lasted until he was 15 when he tried to commit suicide for the second time.

The report's authors first saw the patient several years later. At this point he had been admitted to the psychiatric clinic for his safety and stabilization during an acute crisis with strong, uncontrolled flashbacks, panic attacks and impulses to harm himself. In the past, the self-injuries had resulted in scars from knife cuts. After a few days of stabilizing, he was referred back to a psychotherapy treatment center. In the weeks that followed, his condition improved dramatically. When asked what he believed was responsible for improving his condition, he admitted that he had learned to smoke cannabis resin from other patients. He had discovered that he could prevent divided states of consciousness by smoking cannabis as soon as he noticed the first feelings of reactivation and amplification of traumatic memories as flashbacks. Although he continued to experience flashback phenomena after using cannabis, their course and strength were altered. The authors reviewed the subject and concluded, "There is increasing evidence that cannabinoids may play a role in the extinction of fear and antidepressant effects."

Passie T, Emrich HM, Karst M, Brandt SD, Halpern JH. Mitigation of post-traumatic stress symptoms by Cannabis resin: A review of the clinical and neurobiological evidence. Drug Test Anal. 2012 Jun 26. [in press]